The GPNMB antibody - N-terminal region from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human, Mouse, Rat, Bovine, Canine, Guinea Pig, Horse, and Rabbit antigen. The GPNMB antibody - N-terminal region has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
This is a rabbit polyclonal antibody against GPNMB. It was validated on Western Blot and immunohistochemistry
Target Description: GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential.The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene